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AI Summary: This regulation establishes the White House Great American Recovery Initiative to address the national crisis of addiction, also known as substance use disorder. The initiative, co-chaired by the Secretary of Health and Human Services and the Senior Advisor for Addiction Recovery, aims to coordinate federal government responses, increase public awareness of addiction as a treatable disease, and promote recovery. It will involve various executive departments and agencies, including those responsible for justice, education, labor, housing, and veterans affairs, as well as the Director of National Drug Control Policy and heads of health-related agencies. The initiative will recommend steps to align federal programs, set clear objectives, and provide public updates on progress. It will also advise agencies on integrating prevention, early intervention, treatment, recovery support, and re-entry services across relevant systems, and direct grants to support these efforts, while consulting with state, tribal, local, community, faith-based, private sector, and philanthropic entities.