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AI Summary: This regulation is a policy document. This regulation establishes a comprehensive, whole-of-government approach to accelerate the deployment and commercialization of quantum information science and technology (QIST) in the United States, aiming to solidify the nation's leadership in this transformative field. Key provisions include updating the National Quantum Strategy to support a maturing QIST ecosystem, establishing a national effort to develop a quantum computer for scientific applications (QC-ADDS Effort) and making it available to the scientific community, and prioritizing the development and fielding of next-generation quantum sensors and networks. The regulation also focuses on bolstering the domestic QIST supply chain by analyzing supply chains, encouraging private sector adoption of standards, and supporting research and development for quantum-enabling technologies. Furthermore, it mandates the protection of quantum technology from adversarial threats, the expansion and retention of the quantum workforce through government-wide strategies and training initiatives, and engagement with international partners to ensure access to strategic markets, trusted supply chains, and to prevent adversaries from acquiring critical quantum technologies. The regulation also outlines reporting requirements for various agencies to track progress and inform decision-making.